SCHEMBL28537006

SCHEMBL28537006

CCCC(=O)CCC.CCCC(C)=O

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.53
CES1 P23141 3/20 0.47
CES2 O00748 2/20 0.47
HDAC3 O15379 4/20 0.45
HDAC1 Q13547 4/20 0.45
HDAC2 Q92769 4/20 0.45
HDAC8 Q9BY41 4/20 0.45
FFAR3 O14843 3/20 0.45
TDP1 Q9NUW8 2/20 0.44
TSHR P16473 1/20 0.43
LMNA P02545 1/20 0.43
SLC15A2 Q16348 1/20 0.43
HDAC6 Q9UBN7 1/20 0.39
MAPT P10636 1/20 0.39
KMT2A Q03164 1/20 0.39
IAPP P10997 2/20 0.38
CTSD P07339 1/20 0.38
ACHE P22303 1/20 0.36
PAOX Q6QHF9 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22110900 0.91 ALDH1A1 (0.59) ALDH1A1CES1CES2HDAC3HDAC1
SCHEMBL4084926 0.91 ALDH1A1 (0.59) ALDH1A1CES1CES2HDAC3HDAC1
SCHEMBL865687 0.90
SCHEMBL876374 0.90 ALDH1A1 (0.64) ALDH1A1CES1CES2HDAC3HDAC1
SCHEMBL10577 0.90
Hydrochloric Acid SCHEMBL28498226 0.88 ALDH1A1 (0.56) ALDH1A1CES1CES2HDAC3HDAC1
SCHEMBL11458647 0.88 ALDH1A1 (0.47) ALDH1A1CES1CES2HDAC3HDAC1
Butanone SCHEMBL2972772 0.88 ALDH1A1 (0.62) ALDH1A1CES1CES2HDAC3HDAC1
Acetone SCHEMBL4590814 0.87 CES1 (0.53) ALDH1A1CES1CES2HDAC3HDAC1
Methyl Alcohol SCHEMBL10757259 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109771980-B Heterogeneous azeotropic rectification method for separating mixture of 2-pentanone, 4-heptanone, water and carbon dioxide 中国科学院山西煤炭化学研究所 2021-04-13 CN disclosed
CN-109771980-B Heterogeneous azeotropic rectification method for separating mixture of 2-pentanone, 4-heptanone, water and carbon dioxide 中国科学院山西煤炭化学研究所 2021-04-13 CN disclosed