Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.86 |
| ▸ | DRD3 | P35462 | 2/20 | 0.81 |
| ▸ | HTR1A | P08908 | 1/20 | 0.81 |
| ▸ | HTR2A | P28223 | 1/20 | 0.81 |
| ▸ | HTR7 | P34969 | 1/20 | 0.81 |
| ▸ | HTR6 | P50406 | 1/20 | 0.81 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.81 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.64 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.64 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.64 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.64 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.64 |
| ▸ | DRD4 | P21917 | 1/20 | 0.64 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29473290 | 1.00 | DRD2 (0.86) | DRD2DRD3HTR1AHTR2AHTR7 | |
| SCHEMBL20512964 | 0.92 | DRD2 (1.00) | DRD2DRD3HTR1AHTR2AHTR7 | |
| SCHEMBL23953302 | 0.90 | DRD2 (0.91) | DRD2DRD3HTR1AHTR2AHTR7 | |
| SCHEMBL20512920 | 0.90 | DRD2 (1.00) | DRD2DRD3HTR1AHTR2AHTR7 | |
| SCHEMBL20512968 | 0.88 | DRD2 (1.00) | DRD2DRD3HTR1AHTR2AHTR7 | |
| SCHEMBL20512946 | 0.84 | DRD2 (1.00) | DRD2DRD3HTR1AHTR2AHTR7 | |
| SCHEMBL30179184 | 0.84 | DRD2 (1.00) | DRD2DRD3HTR1AHTR2AHTR7 | |
| SCHEMBL24892665 | 0.84 | DRD2 (0.84) | DRD2DRD3HTR1AHTR2AHTR7 | |
| SCHEMBL24892672 | 0.81 | DRD2 (0.84) | DRD2DRD3HTR1AHTR2AHTR7 | |
| SCHEMBL1835533 | 0.80 | DRD2 (0.71) | DRD2DRD3HTR1AHTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112480102-B | Propionamide derivative and application thereof in schizophrenia | 江苏恩华药业股份有限公司 | 2022-04-22 | — | — | CN | disclosed |
| CN-112480102-A | Propionamide derivative and application thereof in schizophrenia | 江苏恩华药业股份有限公司 | 2021-03-12 | — | — | CN | disclosed |