Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | USP14 | P54578 | 1/20 | 0.40 |
| ▸ | UCHL5 | Q9Y5K5 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | VDR | P11473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4171865 | 0.85 | ESR1 (0.53) | HPGDGAARAB9ACASP3USP14 | |
| SCHEMBL29172301 | 0.84 | HPGD (0.45) | HPGDGAARAB9AMAPTALDH1A1 | |
| SCHEMBL27042944 | 0.83 | HPGD (0.44) | HPGDGAARAB9AMAPTALDH1A1 | |
| SCHEMBL28711869 | 0.83 | GAA (0.47) | HPGDGAARAB9AMAPTALDH1A1 | |
| SCHEMBL20214725 | 0.83 | MAPT (0.47) | HPGDGAARAB9AMAPTALDH1A1 | |
| SCHEMBL4164350 | 0.82 | ESR2 (0.56) | HPGDGAARAB9AMAPTALDH1A1 | |
| SCHEMBL29741541 | 0.82 | ESR2 (0.56) | HPGDGAARAB9AMAPTALDH1A1 | |
| SCHEMBL11318782 | 0.80 | MAPT (0.56) | RAB9AMAPTALDH1A1HTTTHRB | |
| SCHEMBL29172296 | 0.80 | KDM4E (0.44) | HPGDGAARAB9AMAPTALDH1A1 | |
| SCHEMBL27042742 | 0.79 | THRA (0.40) | HPGDGAARAB9AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113307772-B | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2024-06-28 | — | — | CN | disclosed |
| CN-113307772-A | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2021-08-27 | — | — | CN | disclosed |
| CN-106257976-B | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2021-02-02 | — | — | CN | disclosed |