SCHEMBL28537367

SCHEMBL28537367

COc1ccc(C=O)c(OCCCCCCO)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.59
HDAC8 Q9BY41 4/20 0.52
TRIM24 O15164 1/20 0.50
TYR P14679 1/20 0.50
TRIM33 Q9UPN9 1/20 0.50
MAOB P27338 2/20 0.49
ERN1 O75460 2/20 0.46
TLR8 Q9NR97 1/20 0.45
KDM4E B2RXH2 1/20 0.43
RAB9A P51151 1/20 0.43
CYP1A2 P05177 4/20 0.42
CYP1A1 P04798 3/20 0.42
CYP1B1 Q16678 3/20 0.42
MEN1 O00255 1/20 0.42
MAPT P10636 1/20 0.42
KMT2A Q03164 1/20 0.42
NFE2L2 Q16236 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
LMNA P02545 1/20 0.41
CYP2C9 P11712 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5882846 0.90 ALDH1A1 (0.65) ALDH1A1HDAC8TRIM24TYRTRIM33
SCHEMBL8447028 0.88 ALDH1A1 (0.71) ALDH1A1HDAC8TRIM24TYRTRIM33
SCHEMBL8702506 0.87 ALDH1A1 (0.61) ALDH1A1HDAC8TRIM24TYRTRIM33
SCHEMBL17821746 0.87 ALDH1A1 (0.65) ALDH1A1HDAC8TRIM24TYRTRIM33
SCHEMBL8067102 0.85 ALDH1A1 (0.63) ALDH1A1HDAC8TRIM24TYRTRIM33
SCHEMBL13191485 0.85 ALDH1A1 (0.67) ALDH1A1HDAC8TRIM24TYRTRIM33
SCHEMBL7920248 0.85 ALDH1A1 (0.55) ALDH1A1HDAC8TRIM24TYRTRIM33
SCHEMBL20892674 0.82 ALDH1A1 (0.67) ALDH1A1HDAC8TRIM24TYRTRIM33
SCHEMBL11296160 0.82 ALDH1A1 (0.67) ALDH1A1HDAC8TRIM24TYRTRIM33
SCHEMBL28910583 0.82 ALDH1A1 (0.51) ALDH1A1HDAC8TRIM24TYRTRIM33

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112375168-B Side chain rod-shaped polar liquid crystal polymer, preparation method thereof and application thereof in nonlinear optical field 华南理工大学 2022-03-29 CN disclosed
CN-112375168-A Side chain rod-shaped polar liquid crystal polymer, preparation method thereof and application thereof in nonlinear optical field 华南理工大学 2021-02-19 CN disclosed