Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.31 |
| ▸ | SMO | Q99835 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23355478 | 0.81 | MAPT (0.34) | ATRBACE1BACE2SMOCA1 | |
| SCHEMBL21612850 | 0.74 | MAPT (0.33) | ATRBACE1BACE2SMO | |
| SCHEMBL28527024 | 0.74 | EIF4E (0.34) | — | |
| SCHEMBL28527025 | 0.74 | — | — | |
| SCHEMBL21612849 | 0.73 | MAPT (0.33) | ATRBACE1BACE2 | |
| SCHEMBL28526949 | 0.72 | MAP3K14 (0.33) | — | |
| SCHEMBL28534897 | 0.72 | — | — | |
| SCHEMBL24926751 | 0.69 | BRAF (0.40) | SMO | |
| SCHEMBL24926748 | 0.68 | BACE1 (0.36) | ATRBACE1BACE2CA1CA2 | |
| SCHEMBL23355350 | 0.67 | MAPK14 (0.35) | SMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112334460-A | Biaryl ether type quinazoline derivative | 第一三共株式会社 | 2021-02-05 | — | — | CN | disclosed |