SCHEMBL2853774

SCHEMBL2853774

CCOc1ccc(NC(=O)CC(C)=O)cc1

nearest known ligand 0.83

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.83
KMT2A Q03164 6/20 0.72
MEN1 O00255 4/20 0.72
LMNA P02545 1/20 0.72
CYP1A2 P05177 1/20 0.72
TDP1 Q9NUW8 1/20 0.72
MAPT P10636 6/20 0.66
ALDH1A1 P00352 4/20 0.65
SMN1; SMN2 Q16637 3/20 0.65
HTT P42858 1/20 0.65
MAPK1 P28482 1/20 0.65
KDM4E B2RXH2 1/20 0.65
RAB9A P51151 2/20 0.63
NPC1 O15118 1/20 0.63
HPGD P15428 1/20 0.63
FAAH O00519 1/20 0.59
TSHR P16473 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9312707 0.91 POLB (1.00) POLBKMT2AMEN1LMNACYP1A2
SCHEMBL25086 0.88 POLB (0.80) POLBKMT2AMEN1LMNACYP1A2
SCHEMBL4544094 0.87 POLB (0.63) POLBKMT2AMEN1LMNACYP1A2
SCHEMBL4543223 0.87 POLB (0.65) POLBLMNAALDH1A1SMN1; SMN2FAAH
SCHEMBL12445438 0.86 POLB (0.83) POLBKMT2AMEN1LMNACYP1A2
SCHEMBL18778790 0.85 POLB (0.81) POLBKMT2AMEN1LMNACYP1A2
Fenacetinol SCHEMBL2850567 0.84 POLB (0.80) POLBKMT2AMEN1LMNACYP1A2
Phenacetin SCHEMBL18894356 0.84 KMT2A (1.00) POLBKMT2AMEN1LMNACYP1A2
Phenacetin SCHEMBL23280 0.84 KMT2A (1.00) POLBKMT2AMEN1LMNACYP1A2
SCHEMBL11427058 0.84 MAPT (0.61) POLBKMT2AMEN1CYP1A2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114195671-B Asymmetric malonyl aniline compound and synthesis method thereof 河南师范大学 2023-09-22 CN claimed
CN-106278447-B A kind of landscape flower compound organic fertilizer crushes drying system and its working method 徐州工程学院 2019-04-23 CN claimed
CN-106160551-B A kind of wind power generation inversion device and its method of work based on DSP 江苏建筑职业技术学院 2018-05-22 CN claimed
CN-106238984-B A kind of horizontal slide rail formula self-regulated pose bonding machine and its control method 徐州工程学院 2018-01-02 CN claimed
CN-106000270-B The curing agent special reaction device and its production method of a kind of repairing heavy metal in soil pollution 徐州工程学院 2017-09-15 CN claimed
CN-106278447-A A kind of landscape flower compound organic fertilizer pulverizes drying system and method for work thereof 徐州工程学院 2017-01-04 CN claimed
CN-106238984-A A kind of horizontal slide rail formula self-regulated pose bonding machine and control method thereof 徐州工程学院 2016-12-21 CN claimed
CN-106160551-A A kind of wind power generation inversion device based on DSP and method of work thereof 江苏建筑职业技术学院 2016-11-23 CN claimed
CN-106000270-A Special reaction device for curing agent for repair of soil heavy metal pollution and production method thereof 徐州工程学院 2016-10-12 CN claimed
EP-1169393-B1 ACETOACETYLARYLIDE SUSPENSIONS IN PIGMENT APPLICATIONS LONZA AG (CH) 2008-06-11 EP claimed
WO-2000061688-A1 ACETOACETYLARYLIDE SUSPENSIONS IN PIGMENT APPLICATIONS LONZA AG (CH) 2000-10-19 WO claimed
US-6099635-A HOMOGENIZING THE MIXTURE OF ACETOACETARYLIDE WITH ONE OR MORE ADDITIVES TO FORM A SLURRY OF THE ACETOACETARYLIDE LONZA AG (CH) 2000-08-08 US claimed
EP-0610653-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1997-04-16 EP claimed
US-5444036-A Arylsulfonylureido compound, acetoacetanilide compound, sulfonamide derivative; storage stability NEW OIL PAPER CO., LTD. (JP) 1995-08-22 US claimed
EP-0610653-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-08-17 EP claimed
EP-0412121-B1 AZO PIGMENT COMPOSITION HAVING IMPROVED PROCESS HEAT STABILITY AND DRIED INK TRANSPARENCY HOECHST CELANESE CORPORATION (US) 1993-07-28 EP claimed
EP-0412121-A1 AZO PIGMENT COMPOSITION HAVING IMPROVED PROCESS HEAT STABILITY AND DRIED INK TRANSPARENCY. HOECHST CELANESE CORP (US) 1991-02-13 EP claimed
WO-1989010385-A1 AZO PIGMENT COMPOSITION HAVING IMPROVED PROCESS HEAT STABILITY AND DRIED INK TRANSPARENCY HOECHST CELANESE CORPORATION (US) 1989-11-02 WO claimed
US-4780533-A REACTION PRODUCT OF TETRAZO COMPOUND OF 3,3'-DICHLOROBENZIDINE AND ACETOANILIDE DERIVATIVE DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 1988-10-25 US claimed
US-4648907-A 3,3*-DICHLOROBENZIDINE, DIAZOTIZATION, COUPLING, ACETOACETARYLIDES, MULTISTAGE, INKS BASF CORPORATION (US) 1987-03-10 US claimed