SCHEMBL25086

SCHEMBL25086

CCOc1ccc(NC(=O)CN)cc1

nearest known ligand 0.80

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.80
ALDH1A1 P00352 5/20 0.72
KMT2A Q03164 5/20 0.69
MEN1 O00255 4/20 0.69
LMNA P02545 1/20 0.69
CYP1A2 P05177 1/20 0.69
TDP1 Q9NUW8 1/20 0.69
MAPT P10636 6/20 0.68
SMN1; SMN2 Q16637 5/20 0.67
HTT P42858 1/20 0.67
MAPK1 P28482 1/20 0.67
KDM4E B2RXH2 1/20 0.67
NPC1 O15118 3/20 0.65
RAB9A P51151 3/20 0.65
HPGD P15428 1/20 0.65
LTA4H P09960 1/20 0.62
TP53 P04637 1/20 0.60
TSHR P16473 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9312707 0.89 POLB (1.00) POLBALDH1A1KMT2AMEN1LMNA
SCHEMBL2853774 0.88 POLB (0.83) POLBALDH1A1KMT2AMEN1LMNA
SCHEMBL12445438 0.87 POLB (0.83) POLBALDH1A1KMT2AMEN1LMNA
SCHEMBL18778790 0.86 POLB (0.81) POLBALDH1A1KMT2AMEN1LMNA
SCHEMBL11518673 0.86 MEN1 (0.63) POLBALDH1A1KMT2AMEN1LMNA
Fenacetinol SCHEMBL2850567 0.86 POLB (0.80) POLBALDH1A1KMT2AMEN1LMNA
SCHEMBL5808300 0.84 POLB (0.77) POLBALDH1A1KMT2AMEN1LMNA
SCHEMBL9842944 0.84 POLB (0.77) POLBALDH1A1KMT2AMEN1LMNA
SCHEMBL5808296 0.84 POLB (0.77) POLBALDH1A1KMT2AMEN1LMNA
SCHEMBL29270204 0.84 POLB (0.77) POLBALDH1A1KMT2AMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1584 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118206500-A Extraction method of phenamine mycin 上海农乐生物制品股份有限公司 2024-06-18 CN claimed
CN-117729917-A Combination therapy using AKR1C3 activating compounds and immune checkpoint inhibitors 深圳艾欣达伟医药科技有限公司 2024-03-19 CN claimed
CN-113249007-B Primer composition and method of coating a substrate 艾仕得涂料系统有限责任公司 2024-03-15 CN claimed
US-20230285282-A1 OCULAR IMPLANT CONTAINING AN ACTIVE INGREDIENT OCULAR THERAPEUTIX INC (US) 2023-09-14 US claimed
EP-4236943-A1 OCULAR IMPLANT CONTAINING AN ACTIVE AGENT Ocular Therapeutix, Inc. (US) 2023-09-06 EP claimed
CN-116459402-A Nanofiber with unidirectional drainage capability, preparation method and application thereof 四川大学 2023-07-21 CN claimed
CN-113713169-B Near-infrared light-sensitive ZIF8 functionalized gelatin nanofiber scaffold system and application thereof 温州医科大学 2023-07-11 CN claimed
CN-116209475-A Therapeutic uses comprising a triple agonist long-acting conjugate or a combination of triple agonists 韩美药品株式会社 2023-06-02 CN claimed
CN-113880779-B Extraction method of phenamine mycin 上海农乐生物制品股份有限公司 2023-05-05 CN claimed
CN-115709158-A Metal long-acting anticorrosion phenolic amine modified sol-gel film and preparation method thereof 中山大学 2023-02-24 CN claimed
EP-1192129-A2 PHARMACEUTICAL COMPOUNDS NICOX S.A. (FR) 2002-04-03 EP claimed
EP-1169298-A2 PHARMACEUTICAL COMPOUNDS NICOX S.A. (FR) 2002-01-09 EP claimed
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 CN claimed
WO-2001012584-A2 PHARMACEUTICAL COMPOUNDS NICOX S.A. (FR) 2001-02-22 WO claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
WO-2000061541-A2 PHARMACEUTICAL COMPOUNDS NICOX S.A. (FR) 2000-10-19 WO claimed
WO-2000061549-A2 PHARMACEUTICAL COMPOUNDS NICOX S.A. (FR) 2000-10-19 WO claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
CN-1191553-A Method for examining lung disease UNIV NORTH CAROLINA CHAPEL HILL (US) 1998-08-26 CN claimed
CN-1189097-A Dinucleotides for the treatment of pulmonary diseases UNIV NORTH CAROLINA CHAPEL HILL (US) 1998-07-29 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230285282-A1 OCULAR IMPLANT CONTAINING AN ACTIVE INGREDIENT ERBB2, BTK, ERBB3 POLB 4423/4885ALDH1A1 1122/4885KMT2A 1288/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.