Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 2/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9742 | 0.83 | LPAR1 (0.41) | LPAR1LPAR2LPAR3SIGMAR1TSHR | |
| SCHEMBL9860 | 0.83 | LPAR1 (0.37) | LPAR1TSHR | |
| SCHEMBL9813 | 0.80 | LPAR1 (0.39) | LPAR1SIGMAR1TSHR | |
| SCHEMBL9700 | 0.80 | LPAR1 (0.44) | LPAR1LPAR2LPAR3TSHR | |
| SCHEMBL9897 | 0.76 | OPRM1 (0.40) | LPAR1SIGMAR1 | |
| SCHEMBL1607216 | 0.76 | LPAR1 (0.46) | LPAR1LPAR3 | |
| SCHEMBL3312 | 0.76 | LPAR1 (0.46) | LPAR1LPAR3 | |
| SCHEMBL1608181 | 0.76 | LPAR1 (0.46) | LPAR1LPAR3 | |
| SCHEMBL9449 | 0.75 | HTT (0.42) | LPAR1LPAR2LPAR3SIGMAR1TSHR | |
| SCHEMBL10190 | 0.74 | LPAR1 (0.41) | LPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112472699-A | Combination methods for improving the therapeutic benefit of bisantrene and derivatives | 种族肿瘤学公司 | 2021-03-12 | — | — | CN | disclosed |