Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.30 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28535412 | 0.96 | BRD4 (0.39) | BRD4CCNT1CDK9 | |
| SCHEMBL20138007 | 0.81 | CCNT1 (0.34) | BRD4PDE4BBTKCCNT1CDK9 | |
| SCHEMBL20138016 | 0.78 | LMNA (0.34) | PDE4B | |
| SCHEMBL20138162 | 0.77 | PROKR1 (0.35) | BRD4CCNT1CDK9 | |
| SCHEMBL20137992 | 0.77 | TSHR (0.37) | CCNT1CDK9 | |
| SCHEMBL20137925 | 0.76 | KCNK3 (0.36) | BRD4 | |
| SCHEMBL20138149 | 0.74 | BRD4 (0.31) | BRD4 | |
| SCHEMBL20137972 | 0.74 | SLC2A1 (0.30) | — | |
| SCHEMBL20138239 | 0.73 | SLC2A1 (0.35) | BTK | |
| SCHEMBL20138218 | 0.70 | BRD4 (0.30) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107873031-B | Benzoxazinone derivatives and analogs thereof as modulators of TNF activity | UCB生物制药私人有限公司 | 2021-03-12 | — | — | CN | disclosed |