Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Carbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Carbonate SCHEMBL709016 | 0.96 | SMN1; SMN2 (0.37) | SMN1; SMN2CA1CA9 | |
| Propylene Carbonate SCHEMBL1492516 | 0.91 | — | — | |
| Propylene Carbonate SCHEMBL19252610 | 0.91 | — | — | |
| Propylene Carbonate SCHEMBL5134644 | 0.90 | SMN1; SMN2 (0.31) | SMN1; SMN2 | |
| Propylene Carbonate SCHEMBL9129006 | 0.89 | SMN1; SMN2 (0.36) | SMN1; SMN2CA1CA9 | |
| Propylene Carbonate SCHEMBL4729084 | 0.89 | SMN1; SMN2 (0.36) | SMN1; SMN2CA1CA9 | |
| Propylene Carbonate SCHEMBL28294915 | 0.88 | SMN1; SMN2 (0.32) | SMN1; SMN2 | |
| Propylene Carbonate SCHEMBL28144479 | 0.88 | SMN1; SMN2 (0.34) | SMN1; SMN2CA1CA9 | |
| Propylene Carbonate SCHEMBL1954634 | 0.87 | SMN1; SMN2 (0.37) | SMN1; SMN2CA1CA9 | |
| Propylene Carbonate SCHEMBL5861542 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922829-B | Electrochromic element with improved electrolyte layer | 弗劳恩霍夫应用研究促进协会 | 2021-03-16 | — | — | CN | disclosed |