Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Propylene Carbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Carbonate SCHEMBL9129006 | 1.00 | SMN1; SMN2 (0.36) | SMN1; SMN2CA1CA9FFAR3LCK | |
| Propylene Carbonate SCHEMBL1954634 | 0.93 | SMN1; SMN2 (0.37) | SMN1; SMN2CA1CA9 | |
| Propylene Carbonate SCHEMBL709016 | 0.93 | SMN1; SMN2 (0.37) | SMN1; SMN2CA1CA9 | |
| Propylene Carbonate SCHEMBL19252610 | 0.93 | — | — | |
| Propylene Carbonate SCHEMBL28537884 | 0.89 | SMN1; SMN2 (0.34) | SMN1; SMN2CA1CA9 | |
| Propylene Carbonate SCHEMBL5861542 | 0.89 | — | — | |
| Propylene Carbonate SCHEMBL15309 | 0.89 | — | — | |
| Propylene Carbonate SCHEMBL748245 | 0.89 | — | — | |
| Propylene Carbonate SCHEMBL3381047 | 0.89 | — | — | |
| Propylene Carbonate SCHEMBL30481548 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-216310448-U | Progressive-focus glasses with externally-hung prisms | 苏州明世光学科技有限公司 | 2022-04-15 | — | — | CN | claimed |
| CN-101216611-A | Blue ray radiation preventing and achromatism spectacle lens, and method of producing the same | QI ZENG (CN) | 2008-07-09 | — | — | CN | claimed |
| CN-118011535-A | Preparation method and application of protective goggles based on ITO conductive film | 国网河北省电力有限公司超高压分公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-105791789-B | The method of helmet, display equipment and adjust automatically display output | 努比亚技术有限公司 | 2019-03-19 | — | — | CN | disclosed |
| CN-105739099-B | Virtual reality device, display equipment and image adjusting method | 努比亚技术有限公司 | 2019-03-08 | — | — | CN | disclosed |
| CN-106406536-A | Head device, display device and image display method | 努比亚技术有限公司 | 2017-02-15 | — | — | CN | disclosed |
| CN-106028013-A | Wearable device, display device, and display output adjusting method | 努比亚技术有限公司 | 2016-10-12 | — | — | CN | disclosed |
| CN-103635462-B | Method for producing (meth) acrylic esters | 巴斯夫欧洲公司 | 2016-09-14 | — | — | CN | disclosed |
| CN-105791789-A | Head-mounted equipment, display equipment and method of automatically adjusting display output | 努比亚技术有限公司 | 2016-07-20 | — | — | CN | disclosed |
| CN-105739099-A | Virtual reality equipment, display equipment and image adjusting method | 努比亚技术有限公司 | 2016-07-06 | — | — | CN | disclosed |
| CN-101216611-A | Blue ray radiation preventing and achromatism spectacle lens, and method of producing the same | QI ZENG (CN) | 2008-07-09 | — | — | CN | disclosed |
| WO-2008042325-A1 | IMPROVED WATER DISPERSIBLE POLYISOCYANATES | RHODIA INC. (US) | 2008-04-10 | — | — | WO | disclosed |
| US-4312930-A | MANGANESE DIOXIDE FROM LITHIUM MANGANATE SPINEL | UNION CARBIDE CORPORATION (US) | 1982-01-26 | — | — | US | disclosed |