Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FERMT2 | Q96AC1 | 3/20 | 0.49 |
| ▸ | MPO | P05164 | 5/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | NSD3 | Q9BZ95 | 2/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | SYK | P43405 | 2/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6661655 | 0.84 | FERMT2 (0.53) | FERMT2 | |
| SCHEMBL28529691 | 0.83 | ADRB2 (0.40) | FERMT2SYKAAK1 | |
| SCHEMBL25820070 | 0.75 | FERMT2 (0.47) | FERMT2NSD3NSD2MYCAAK1 | |
| SCHEMBL30149344 | 0.70 | FERMT2 (0.50) | FERMT2NSD3NSD2MYCAAK1 | |
| SCHEMBL26220553 | 0.70 | FERMT2 (0.50) | FERMT2NSD3NSD2MYCAAK1 | |
| SCHEMBL24338479 | 0.70 | FERMT2 (0.50) | FERMT2NSD3NSD2MYCAAK1 | |
| SCHEMBL30174534 | 0.70 | FERMT2 (0.50) | FERMT2NSD3NSD2MYCAAK1 | |
| SCHEMBL24338855 | 0.70 | FERMT2 (0.50) | FERMT2NSD3NSD2MYCAAK1 | |
| SCHEMBL16568038 | 0.68 | KCNH2 (0.61) | — | |
| SCHEMBL18825588 | 0.67 | FERMT2 (0.44) | FERMT2MPONSD3NSD2MYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113527201-A | Optically active chloroquine and hydroxychloroquine and analogs thereof, preparation method, composition and application thereof | 瀚海新拓(杭州)生物医药有限公司 | 2021-10-22 | — | — | CN | disclosed |
| CN-112457244-A | Optically active chloroquine and hydroxychloroquine and analogs thereof, preparation method, composition and application thereof | 瀚海新拓(杭州)生物医药有限公司 | 2021-03-09 | — | — | CN | disclosed |