Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18243384 | 0.77 | PLAU (0.38) | IDO1CYP11B2PLAUTSHR | |
| SCHEMBL28139148 | 0.77 | PARP1 (0.36) | IDO1KDM4EL3MBTL1CYP19A1CYP11B1 | |
| SCHEMBL6143052 | 0.71 | IDO1 (0.43) | IDO1PLAU | |
| SCHEMBL22554804 | 0.71 | CYP19A1 (0.39) | IDO1KDM4EL3MBTL1CYP19A1CYP11B1 | |
| SCHEMBL1702930 | 0.71 | CYP19A1 (0.39) | IDO1KDM4EL3MBTL1CYP19A1CYP11B1 | |
| SCHEMBL23457245 | 0.71 | IDO1 (0.38) | IDO1KDM4EL3MBTL1CYP19A1CYP11B1 | |
| SCHEMBL583647 | 0.71 | IDO1 (0.38) | IDO1KDM4EL3MBTL1CYP19A1CYP11B1 | |
| SCHEMBL151547 | 0.71 | IDO1 (0.38) | IDO1KDM4EL3MBTL1CYP19A1CYP11B1 | |
| SCHEMBL17765425 | 0.71 | IDO1 (0.38) | IDO1KDM4EL3MBTL1CYP19A1CYP11B1 | |
| SCHEMBL1040813 | 0.71 | IDO1 (0.38) | IDO1KDM4EL3MBTL1CYP19A1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010047826-A2 | DOSING REGIMENS AND DOSAGE FORMULATIONS OF AN ANTIVIRAL PEPTIDE THERAPEUTIC | TRIMERIS, INC. (US) | 2010-04-29 | — | — | WO | disclosed |
| CN-1898254-A | New coupling agents for peptide synthesis | UNIV MASSACHUSETTS (US) | 2007-01-17 | — | — | CN | disclosed |