Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 4/20 | 0.34 |
| ▸ | HTR2C | P28335 | 4/20 | 0.34 |
| ▸ | HTR2B | P41595 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22554804 | 1.00 | CYP19A1 (0.39) | CYP19A1CYP11B1CYP11B2IDO1ACHE | |
| SCHEMBL30317868 | 0.77 | CYP19A1 (0.37) | CYP19A1CYP11B1CYP11B2IDO1ACHE | |
| SCHEMBL15049696 | 0.77 | MAOB (0.39) | IDO1 | |
| SCHEMBL8161816 | 0.77 | CYP19A1 (0.37) | CYP19A1CYP11B1CYP11B2IDO1ACHE | |
| SCHEMBL9533578 | 0.76 | PRCP (0.35) | CYP19A1CYP11B1CYP11B2IDO1ACHE | |
| SCHEMBL23457245 | 0.71 | IDO1 (0.38) | CYP19A1CYP11B1CYP11B2IDO1KDM4E | |
| SCHEMBL583647 | 0.71 | IDO1 (0.38) | CYP19A1CYP11B1CYP11B2IDO1KDM4E | |
| SCHEMBL151547 | 0.71 | IDO1 (0.38) | CYP19A1CYP11B1CYP11B2IDO1KDM4E | |
| SCHEMBL6143052 | 0.71 | IDO1 (0.43) | IDO1HTR2ANOS3NOS2 | |
| SCHEMBL2853835 | 0.71 | IDO1 (0.38) | CYP19A1CYP11B1CYP11B2IDO1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240174776-A1 | SPHERICAL CATALYST COMPONENTS FOR OLEFIN POLYMERIZATION | W.R. GRACE & CO.-CONN. (US) | 2024-05-30 | — | — | US | disclosed |
| US-11891460-B2 | Activated catalyst components for olefin polymerization | W. R. GRACE & CO.-CONN. (US) | 2024-02-06 | — | — | US | disclosed |
| EP-4308615-A1 | SPHERICAL CATALYST COMPONENTS FOR OLEFIN POLYMERIZATION | W. R. Grace & Co.-Conn (US) | 2024-01-24 | — | — | EP | disclosed |
| EP-3464391-B1 | NON-PHTHALATE DONOR FOR POLYOLEFIN CATALYSTS | BRASKEM AMERICA INC (US) | 2024-01-03 | — | — | EP | disclosed |
| EP-3240814-B1 | CATALYST SYSTEMS, OLEFIN POLYMERIZATION CATALYST COMPONENTS COMPRISING AT LEAST AN INTERNAL ELECTRON DONOR COMPOUND, AND METHODS OF MAKING AND USING THE SAME | BRASKEM AMERICA INC (US) | 2023-10-18 | — | — | EP | disclosed |
| EP-3877372-B1 | ENANTIOSELECTIVE REDUCTION OF OXIME-DERIVATIVES INVOLVING IRIDIUM BASED CATALYSTS | SYNGENTA CROP PROTECTION AG (CH) | 2023-08-02 | — | — | EP | disclosed |
| EP-2785752-B1 | INTERNAL ELECTRON DONOR FOR OLEFIN POLYMERIZATION CATALYSTS, METHOD OF MAKING AND USING THE SAME | BRASKEM AMERICA INC (US) | 2023-05-31 | — | — | EP | disclosed |
| US-11634520-B2 | Catalyst components for propylene polymerization | W.R. GRACE & CO.-CONN. (US) | 2023-04-25 | — | — | US | disclosed |
| WO-2022197491-A1 | SPHERICAL CATALYST COMPONENTS FOR OLEFIN POLYMERIZATION | W.R. GRACE & CO.-CONN. (US) | 2022-09-22 | — | — | WO | disclosed |
| US-11421056-B2 | Polyolefin polymer composition | W.R. GRACE & CO.-CONN. (US) | 2022-08-23 | — | — | US | disclosed |
| US-5021414-A | Antiestrogen | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-06-04 | — | — | US | disclosed |
| US-4990479-A | Coordination catalysts | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-02-05 | — | — | US | disclosed |
| US-4921955-A | Process for the synthesis of 1-substituted imidazole-5-carboxylic acids and carboxylic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1990-05-01 | — | — | US | disclosed |
| US-4904661-A | ANTIESTROGENS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-02-27 | — | — | US | disclosed |
| EP-0350170-A2 | Process for polymerising olefins and polymerisation catalyst therefor | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1990-01-10 | — | — | EP | disclosed |
| EP-0314852-A2 | Process for the preparation of 1-substituted imidazole-carbonic acid and derivatives | CIBA-GEIGY AG (CH) | 1989-05-10 | — | — | EP | disclosed |
| US-4732912-A | ANTIESTROGENS, ANTITUMOR AGENTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-03-22 | — | — | US | disclosed |
| US-4730060-A | ANTIULCER, ANTITHROMBOTIC, HYPOTENSIVE | KOTOBUKI SEIYAKU CO. LTD. (JP) | 1988-03-08 | — | — | US | disclosed |
| EP-0124369-B1 | PHENOL DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-06-24 | — | — | EP | disclosed |
| EP-0124369-A1 | Phenol derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-11-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11634520-B2 | Catalyst components for propylene polymerization | PPIP5K2, PHPT1, PPOX | CYP19A1 326/4885CYP11B1 1856/4885CYP11B2 1349/4885 |
| US-11421056-B2 | Polyolefin polymer composition | ETV6, PUF60, ELL | CYP19A1 1014/4885CYP11B1 3326/4885CYP11B2 3221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.