SCHEMBL28538370

SCHEMBL28538370

NNC(=O)CCSCCC(=O)NCc1ccc(CO)c([N+](=O)[O-])c1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.48
ALDH1A1 P00352 2/20 0.48
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
LMNA P02545 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
TP53 P04637 1/20 0.37
POLB P06746 2/20 0.36
KDM4E B2RXH2 1/20 0.36
HPGD P15428 1/20 0.36
PTPN7 P35236 1/20 0.36
HSD17B10 Q99714 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29113836 0.90 TPSAB1 (0.43) ALDH1A1NPC1RAB9ALMNASMN1; SMN2
SCHEMBL30541778 0.87 NPC1 (0.44) MAPTALDH1A1NPC1RAB9ALMNA
SCHEMBL28538471 0.81 CXCR4 (0.48) ALDH1A1NPC1RAB9AKDM4E
SCHEMBL28539799 0.80 NPC1 (0.39) MAPTALDH1A1NPC1RAB9ALMNA
SCHEMBL28541574 0.79 HDAC3 (0.52) MAPTALDH1A1
SCHEMBL28535807 0.78 NPC1 (0.46) MAPTALDH1A1NPC1RAB9ALMNA
SCHEMBL28536922 0.78 NPC1 (0.46) MAPTALDH1A1NPC1RAB9ALMNA
SCHEMBL29450344 0.78 CYP2C19 (0.45) NPC1RAB9ALMNASMN1; SMN2HPGD
SCHEMBL28539403 0.76 NPC1 (0.41) ALDH1A1NPC1RAB9ALMNASMN1; SMN2
Hydrochloric Acid SCHEMBL29113808 0.75 MEN1 (0.45) ALDH1A1NPC1RAB9APOLBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112574089-B Photo-induced multifunctional crosslinking agent, preparation method and application thereof 中国科学院上海药物研究所 2023-09-05 CN disclosed
CN-112574089-A Photoinduced multifunctional cross-linking agent, and preparation method and application thereof 中国科学院上海药物研究所 2021-03-30 CN disclosed