Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.56 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | MAT2A | P31153 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
| ▸ | CTSA | P10619 | 3/20 | 0.38 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.38 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28355309 | 0.83 | PDPK1 (0.53) | PDPK1SLC6A9PTGDR2CYP2A6ADRB2 | |
| SCHEMBL13393593 | 0.78 | SRC (0.47) | PDPK1ADRB2LOXL2 | |
| SCHEMBL1047236 | 0.78 | PDPK1 (0.53) | PDPK1CYP2A6ADRB2LOXL2CTSA | |
| SCHEMBL26135624 | 0.78 | PDPK1 (0.65) | PDPK1SLC6A9KDRPTGDR2CYP2A6 | |
| SCHEMBL5147639 | 0.77 | PDPK1 (0.91) | PDPK1SLC6A9KDRPTGDR2CYP2A6 | |
| SCHEMBL4425765 | 0.76 | PDPK1 (0.74) | PDPK1SLC6A9KDRPTGDR2CYP2A6 | |
| SCHEMBL4047151 | 0.76 | PDPK1 (0.39) | PDPK1KDRCYP2A6ADRB2LOXL2 | |
| SCHEMBL28279316 | 0.76 | PDPK1 (0.47) | PDPK1CYP2A6MAT2APLA2G7ENPP3 | |
| SCHEMBL7588401 | 0.76 | HSP90AA1 (0.41) | PDPK1CYP2A6ADRB2LOXL2 | |
| SCHEMBL2175845 | 0.74 | PDPK1 (0.70) | PDPK1SLC6A9KDRPTGDR2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110204507-B | Process for producing 2-aryl-4-alkylthiazole compound | 浙江大学 | 2021-03-02 | — | — | CN | disclosed |