Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.53 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | EDNRB | P24530 | 1/20 | 0.41 |
| ▸ | EDNRA | P25101 | 1/20 | 0.41 |
| ▸ | CTSA | P10619 | 1/20 | 0.40 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1047236 | 0.94 | PDPK1 (0.53) | PDPK1PLA2G7ADRB2LOXL2CYP2A6 | |
| SCHEMBL28538440 | 0.83 | PDPK1 (0.56) | PDPK1PLA2G7ADRB2LOXL2CYP2A6 | |
| SCHEMBL9089977 | 0.81 | PDPK1 (0.52) | PDPK1PLA2G7ADRB2LOXL2CYP2A6 | |
| SCHEMBL5692672 | 0.80 | PDPK1 (0.64) | PDPK1ADRB2LOXL2CYP2A6ADRA1A | |
| SCHEMBL11211014 | 0.80 | PDPK1 (0.46) | PDPK1PLA2G7ADRB2LOXL2CYP2A6 | |
| SCHEMBL1951149 | 0.78 | PDPK1 (0.61) | PDPK1ADRB2LOXL2CYP2A6ADRA1A | |
| SCHEMBL996777 | 0.76 | PDPK1 (0.53) | PDPK1ADRB2LOXL2CYP2A6ADRA1A | |
| SCHEMBL2175845 | 0.76 | PDPK1 (0.70) | PDPK1ADRB2LOXL2CYP2A6ADRA1A | |
| SCHEMBL17030749 | 0.75 | PDPK1 (0.48) | PDPK1PLA2G7ADRB2LOXL2CYP2A6 | |
| SCHEMBL5147639 | 0.75 | PDPK1 (0.91) | PDPK1ADRB2LOXL2CYP2A6SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110627739-B | Method for synthesizing thiazole heterocyclic compound through photocatalysis | 桂林医学院 | 2023-02-07 | — | — | CN | disclosed |
| CN-110627739-A | Method for synthesizing thiazole heterocyclic compound through photocatalysis | 桂林医学院 | 2019-12-31 | — | — | CN | disclosed |