SCHEMBL28538468

SCHEMBL28538468

CCCCOC(=O)NCF

nearest known ligand 0.60

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ACHE P22303 14/20 0.60
EPHX1 P07099 1/20 0.52
ALDH1A1 P00352 1/20 0.50
ATM Q13315 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL970930 0.83 ACHE (0.64) ACHEEPHX1ALDH1A1ATM
SCHEMBL11411528 0.83 ACHE (0.64) ACHEEPHX1ALDH1A1ATM
SCHEMBL606985 0.81 ACHE (0.62) ACHEEPHX1ALDH1A1ATM
SCHEMBL7569673 0.81 ACHE (0.81) ACHEEPHX1
SCHEMBL606986 0.81 ACHE (0.62) ACHEEPHX1ALDH1A1ATM
SCHEMBL8381680 0.81 ACHE (0.74) ACHEEPHX1ALDH1A1
SCHEMBL10939707 0.81 ACHE (0.81) ACHEEPHX1
SCHEMBL3975468 0.81 ACHE (0.88) ACHEEPHX1
SCHEMBL2853012 0.79 ACHE (0.85) ACHEEPHX1
SCHEMBL473096 0.79 ACHE (0.85) ACHEEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112566934-A B7-H4 antibodies and methods of use thereof 奈斯科尔公司 2021-03-26 CN disclosed