Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.75 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.75 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.75 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.75 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.75 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.75 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.75 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.75 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.75 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 9/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL229039 | 0.96 | HDAC6 (0.82) | HDAC6HDAC1HDAC3HDAC4HDAC2 | |
| SCHEMBL29988092 | 0.96 | HDAC6 (0.82) | HDAC6HDAC1HDAC3HDAC4HDAC2 | |
| SCHEMBL12102424 | 0.91 | HDAC6 (0.71) | HDAC6HDAC1HDAC3HDAC4HDAC2 | |
| SCHEMBL30714411 | 0.91 | HDAC6 (0.92) | HDAC6HDAC1HDAC3HDAC4HDAC2 | |
| SCHEMBL226988 | 0.91 | HDAC6 (0.92) | HDAC6HDAC1HDAC3HDAC4HDAC2 | |
| SCHEMBL28548077 | 0.90 | HDAC6 (0.92) | HDAC6HDAC1HDAC3HDAC4HDAC2 | |
| SCHEMBL14816587 | 0.90 | HDAC6 (0.92) | HDAC6HDAC1HDAC3HDAC4HDAC2 | |
| Hydrochloric Acid SCHEMBL2783279 | 0.90 | HDAC6 (0.90) | HDAC6HDAC1HDAC3HDAC4HDAC2 | |
| SCHEMBL16772708 | 0.89 | HDAC6 (0.94) | HDAC6HDAC1HDAC3HDAC4HDAC2 | |
| SCHEMBL15396385 | 0.88 | HDAC6 (0.70) | HDAC6HDAC1HDAC3HDAC4HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112624980-B | Preparation method of bendamustine hydrochloride suitable for industrial production | 深圳万乐药业有限公司 | 2022-10-04 | — | — | CN | claimed |
| CN-112624980-A | Preparation method of bendamustine hydrochloride suitable for industrial production | 深圳万乐药业有限公司 | 2021-04-09 | — | — | CN | claimed |
| CN-112624980-B | Preparation method of bendamustine hydrochloride suitable for industrial production | 深圳万乐药业有限公司 | 2022-10-04 | — | — | CN | disclosed |
| CN-112624980-A | Preparation method of bendamustine hydrochloride suitable for industrial production | 深圳万乐药业有限公司 | 2021-04-09 | — | — | CN | disclosed |