Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28532595 | 0.71 | PDE2A (0.33) | PDE2A | |
| SCHEMBL19868200 | 0.65 | — | — | |
| SCHEMBL21590039 | 0.54 | ALDH1A1 (0.41) | — | |
| SCHEMBL16055562 | 0.53 | IKBKB (0.31) | — | |
| SCHEMBL24127040 | 0.53 | ALDH1A1 (0.40) | — | |
| SCHEMBL10189311 | 0.52 | PDE2A (0.70) | PDE2A | |
| SCHEMBL24118137 | 0.52 | PTPN5 (0.42) | PDE2A | |
| SCHEMBL24117855 | 0.52 | KDM4E (0.33) | — | |
| SCHEMBL21737375 | 0.51 | EIF4A3 (0.31) | — | |
| SCHEMBL1147216 | 0.51 | PDE2A (0.57) | PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114621233-A | Substituted aromatic condensed ring derivative and its composition and use | 深圳市塔吉瑞生物医药有限公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-112552302-B | Substituted aromatic fused ring derivatives, compositions and uses thereof | 深圳市塔吉瑞生物医药有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-112552302-A | Substituted aromatic fused ring derivatives, compositions and uses thereof | 深圳市塔吉瑞生物医药有限公司 | 2021-03-26 | — | — | CN | disclosed |