SCHEMBL28538677

SCHEMBL28538677

NCCC[C@@H](NC(=O)CCl)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 2/20 0.51
GNPAT O15228 1/20 0.47
SLC6A5 Q9Y345 1/20 0.47
NOD1 Q9Y239 7/20 0.42
SLC15A2 Q16348 1/20 0.40
CPB2 Q96IY4 2/20 0.40
GGT1 P19440 1/20 0.39
GSR P00390 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
C3AR1 Q16581 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22776222 1.00 FOLH1 (0.51) FOLH1GNPATSLC6A5NOD1SLC15A2
SCHEMBL22776223 1.00 FOLH1 (0.51) FOLH1GNPATSLC6A5NOD1SLC15A2
SCHEMBL20477195 0.95 FOLH1 (0.58) FOLH1GNPATSLC6A5NOD1SLC15A2
SCHEMBL5215821 0.95 FOLH1 (0.58) FOLH1GNPATSLC6A5NOD1SLC15A2
SCHEMBL11708581 0.95 FOLH1 (0.58) FOLH1GNPATSLC6A5NOD1SLC15A2
SCHEMBL27860271 0.85 FOLH1 (0.54) FOLH1GNPATSLC6A5NOD1SLC15A2
SCHEMBL2114736 0.85 FOLH1 (0.54) FOLH1GNPATSLC6A5NOD1SLC15A2
SCHEMBL2114733 0.85 FOLH1 (0.54) FOLH1GNPATSLC6A5NOD1SLC15A2
SCHEMBL30834826 0.83 FOLH1 (0.57) FOLH1GNPATSLC6A5NOD1SLC15A2
SCHEMBL3223579 0.83 FOLH1 (0.53) FOLH1GNPATSLC6A5NOD1SLC15A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112566928-A Super-generic method for conferring novel binding specificities to antibodies 国立大学法人东京大学 2021-03-26 CN disclosed