Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.39 |
| ▸ | PPARA | Q07869 | 4/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.37 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856120 | 0.89 | PPARG (0.40) | PPARGPPARAPPARDADAMTS4ADAMTS5 | |
| SCHEMBL6155894 | 0.87 | PPARG (0.40) | PPARGPPARAPPARD | |
| SCHEMBL2853874 | 0.86 | PPARG (0.41) | PPARGPPARAPPARDADAMTS4ADAMTS5 | |
| SCHEMBL2855546 | 0.82 | PPARG (0.43) | PPARGPPARAPPARDADAMTS4ADAMTS5 | |
| SCHEMBL2855544 | 0.82 | PPARG (0.43) | PPARGPPARAPPARDADAMTS4ADAMTS5 | |
| SCHEMBL6155236 | 0.82 | PPARG (0.40) | PPARGPPARAPPARDADAMTS4ADAMTS5 | |
| SCHEMBL2852205 | 0.82 | PPARG (0.41) | PPARGPPARAPPARD | |
| SCHEMBL2852203 | 0.82 | PPARG (0.41) | PPARGPPARAPPARD | |
| SCHEMBL2856242 | 0.82 | PPARG (0.44) | PPARGPPARAPPARDADAMTS4ADAMTS5 | |
| SCHEMBL2856957 | 0.82 | PPARG (0.44) | PPARGPPARAPPARDADAMTS4ADAMTS5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575911-B1 | BIAROMATIC COMPOUNDS WHICH ACTIVATE PPAR-GAMMA TYPE RECEPTORS AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RES & DEV (FR) | 2010-01-13 | — | — | EP | claimed |