Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 19/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.37 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2855544 | 0.84 | PPARG (0.43) | PPARGPPARAPPARDADAMTS4ADAMTS5 | |
| SCHEMBL2855546 | 0.84 | PPARG (0.43) | PPARGPPARAPPARDADAMTS4ADAMTS5 | |
| SCHEMBL2856120 | 0.82 | PPARG (0.40) | PPARGPPARAPPARDADAMTS4ADAMTS5 | |
| SCHEMBL2853877 | 0.82 | PPARG (0.39) | PPARGPPARAPPARDADAMTS4ADAMTS5 | |
| SCHEMBL2853874 | 0.82 | PPARG (0.41) | PPARGPPARAPPARDADAMTS4ADAMTS5 | |
| SCHEMBL2856957 | 0.81 | PPARG (0.44) | PPARGPPARAPPARDADAMTS4ADAMTS5 | |
| SCHEMBL2856242 | 0.81 | PPARG (0.44) | PPARGPPARAPPARDADAMTS4ADAMTS5 | |
| SCHEMBL6155894 | 0.78 | PPARG (0.40) | PPARGPPARAPPARD | |
| SCHEMBL2852205 | 0.77 | PPARG (0.41) | PPARGPPARAPPARD | |
| SCHEMBL2852203 | 0.77 | PPARG (0.41) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575911-A2 | BIAROMATIC COMPOUNDS WHICH ACTIVATE PPAR-GAMMA TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | Galderma Research & Development, S.N.C. (FR) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004046091-A2 | BIAROMATIC COMPOUNDS WHICH ACTIVATE PPAR-GAMA TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-06-03 | — | — | WO | disclosed |