Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 17/20 | 0.56 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28533927 | 0.91 | EGFR (0.66) | EGFR | |
| SCHEMBL28529546 | 0.91 | EGFR (0.56) | EGFRPLK1ALK | |
| SCHEMBL22821808 | 0.89 | EGFR (0.70) | EGFR | |
| SCHEMBL28542494 | 0.85 | EGFR (0.67) | EGFR | |
| SCHEMBL28531481 | 0.84 | EGFR (0.61) | EGFR | |
| SCHEMBL28538584 | 0.84 | EGFR (0.66) | EGFRALK | |
| SCHEMBL22026205 | 0.83 | EGFR (0.69) | EGFRALK | |
| SCHEMBL28908567 | 0.82 | EGFR (0.54) | EGFRPLK1ALK | |
| SCHEMBL28529304 | 0.82 | EGFR (0.64) | EGFR | |
| SCHEMBL22804181 | 0.82 | EGFR (0.68) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513029-B | Nitrogen-containing aryl phosphorus oxide derivative, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-10-24 | — | — | CN | disclosed |
| CN-112513029-A | Nitrogen-containing aryl phosphorus oxide derivative, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2021-03-16 | — | — | CN | disclosed |