SCHEMBL28539828

SCHEMBL28539828

O=C(CCSCCC(=O)ON1OCCO1)OCc1ccc(CO)c([N+](=O)[O-])c1

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.33
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
TDP1 Q9NUW8 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
MAPK1 P28482 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
RAB9A P51151 2/20 0.31
S1PR1 P21453 1/20 0.31
S1PR5 Q9H228 1/20 0.31
PAX8 Q06710 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29113844 0.94 ALDH1A1 (0.33) ALDH1A1MEN1KMT2ATDP1CYP1A2
SCHEMBL29113825 0.94 ALDH1A1 (0.36) ALDH1A1MEN1KMT2ATDP1CYP1A2
SCHEMBL30541772 0.91 ALDH1A1 (0.39) ALDH1A1MEN1KMT2ATDP1CYP1A2
SCHEMBL29113819 0.89 ALDH1A1 (0.35) ALDH1A1MEN1KMT2ATDP1CYP1A2
SCHEMBL28539799 0.87 NPC1 (0.39) ALDH1A1MEN1KMT2ATDP1RAB9A
SCHEMBL29113847 0.86 ALDH1A1 (0.36) ALDH1A1MEN1KMT2ATDP1CYP1A2
SCHEMBL28535829 0.85 EPHX2 (0.35) ALDH1A1MEN1KMT2ATDP1CYP1A2
SCHEMBL29113810 0.82 ALDH1A1 (0.36) ALDH1A1TDP1MAPK1S1PR1S1PR5
SCHEMBL29113833 0.81 NPC1 (0.39) ALDH1A1MEN1KMT2ATDP1CYP1A2
SCHEMBL28910177 0.78 ALDH1A1 (0.48) ALDH1A1MEN1KMT2ATDP1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112574089-B Photo-induced multifunctional crosslinking agent, preparation method and application thereof 中国科学院上海药物研究所 2023-09-05 CN disclosed
CN-112574089-A Photoinduced multifunctional cross-linking agent, and preparation method and application thereof 中国科学院上海药物研究所 2021-03-30 CN disclosed