Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL701217 | 0.94 | TSHR (0.52) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| Ethylene SCHEMBL9786557 | 0.93 | TSHR (0.50) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| Propane SCHEMBL28542029 | 0.89 | TSHR (0.52) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| Benzene SCHEMBL28459736 | 0.89 | THRB (0.47) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL12570577 | 0.84 | TSHR (0.66) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL12570584 | 0.84 | TSHR (0.66) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL12570582 | 0.84 | TSHR (0.66) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL12570585 | 0.84 | TSHR (0.66) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL2461678 | 0.84 | TSHR (0.59) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL12570583 | 0.81 | TSHR (0.66) | TSHRALDH1A1TP53HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109988261-B | Cyclized polymer containing ureido macrocycle, and preparation method and application thereof | 南华大学 | 2021-02-12 | — | — | CN | disclosed |