Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | VCP | P55072 | 1/20 | 0.39 |
| ▸ | HNF4A | P41235 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | PAM | P19021 | 1/20 | 0.37 |
| ▸ | HAO1 | Q9UJM8 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31454048 | 0.89 | MAPT (0.47) | MAPTNPSR1FFAR1NPC1RAB9A | |
| SCHEMBL38664095 | 0.87 | MAPT (0.42) | MAPTNPSR1FFAR1NPC1RAB9A | |
| SCHEMBL28977971 | 0.85 | ALDH1A1 (0.47) | MAPTNPSR1FFAR1NPC1RAB9A | |
| SCHEMBL28977961 | 0.84 | CA12 (0.41) | MAPTFFAR1RAB9AMEN1KMT2A | |
| SCHEMBL26939701 | 0.83 | ELANE (0.42) | MAPTNPSR1FFAR1NPC1RAB9A | |
| SCHEMBL28546563 | 0.82 | ACACB (0.40) | MAPTNPSR1NPC1RAB9AMEN1 | |
| SCHEMBL23183062 | 0.82 | MAPT (0.42) | MAPTNPSR1FFAR1APPVCP | |
| SCHEMBL28541057 | 0.82 | FFAR1 (0.47) | FFAR1HAO1 | |
| SCHEMBL26939288 | 0.82 | MAPT (0.42) | MAPTNPSR1FFAR1NPC1RAB9A | |
| SCHEMBL13896340 | 0.80 | MAPT (0.41) | MAPTNPSR1FFAR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109678854-B | Method for synthesizing pyrido [1,2-a ] indole-6 (1H) -ketone compound by manganese catalysis | 陕西师范大学 | 2021-04-09 | — | — | CN | disclosed |