Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 9/20 | 0.70 |
| ▸ | CA4 | P22748 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 4/20 | 0.44 |
| ▸ | CES1 | P23141 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 8/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL1033231 | 0.91 | CA2 (0.76) | CA2CA4LMNAMAPTXBP1 | |
| Benzoic Acid SCHEMBL1535463 | 0.88 | CA2 (0.89) | CA2CA4LMNAMAPTSMN1; SMN2 | |
| Benzoic Acid SCHEMBL115644 | 0.88 | CA2 (0.89) | CA2CA4LMNAMAPTSMN1; SMN2 | |
| Benzoic Acid SCHEMBL7210053 | 0.87 | CA2 (0.64) | CA2CA4LMNAMAPTXBP1 | |
| Benzoic Acid SCHEMBL29019191 | 0.86 | CA2 (0.70) | CA2CA4LMNAMAPTXBP1 | |
| Benzoic Acid SCHEMBL31683009 | 0.86 | CA2 (0.70) | CA2CA4LMNAMAPTXBP1 | |
| Benzoic Acid SCHEMBL11054341 | 0.86 | CA2 (0.76) | CA2CA4CES2CES1TSHR | |
| Benzoic Acid SCHEMBL11652817 | 0.85 | CA2 (0.84) | CA2CA4LMNAMAPTSMN1; SMN2 | |
| Benzoic Acid SCHEMBL11441689 | 0.85 | CA2 (0.84) | CA2CA4MAPTSMN1; SMN2CES2 | |
| Benzoic Acid SCHEMBL28569088 | 0.85 | CA2 (0.84) | CA2CA4LMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1179569-B1 | Silicone composition and electrically conductive cured silicone product | DOW CORNING (US) | 2010-01-13 | — | — | EP | disclosed |
| US-6831145-B2 | Used in manufacture of electronic, construction, appliance, and aerospace products; coating, adhesive, or gasket | DOW CORNING CORPORATION | 2004-12-14 | — | — | US | disclosed |
| US-20030008955-A1 | Silicone composition and electrically conductive, cured silicone product | DOLBY LABORATORIES LICENSING CORPORATION | 2003-01-09 | — | — | US | disclosed |
| US-6465550-B1 | POLYSILOXANE WITH TERMINAL EPOXY FUNCTIONAL GROUPS, PHENOL FREE CURING AGENT, FILLER OF SUCH AS SILVER, GOLD, PLATINUM AND/OR PALLADIUM AND HYROXYLATED COMPOUND; ELECTRONICS, CONSTRUCTION MATERIALS, APPLIANCES, AEROSPACE | DOW CORNING CORPORATION | 2002-10-15 | — | — | US | disclosed |
| EP-1179569-A2 | Silicone composition and electrically conductive cured silicone product | DOW CORNING CORPORATION (US) | 2002-02-13 | — | — | EP | disclosed |
| US-RE31543-E | EPOXIDE, SILOXANE, ALUMINUM CATALYST | DOW CORNING CORPORATION (US) | 1984-03-27 | — | — | US | disclosed |
| US-4202811-A | USED TO ENCAPSULATE ELECTRONIC DEVICES | DOW CORNING CORPORATION (US) | 1980-05-13 | — | — | US | disclosed |
| US-4082719-A | ORGANOSILICON AND ALUMINUM COMPOUNDS, CURING CATALYST | DOW CORNING CORPORATION (US) | 1978-04-04 | — | — | US | disclosed |
| US-3971747-A | ORGANO-SILICON, EPOXIDE, ALUMINUM CONTAINING CATALYST | DOW CORNING CORPORATION (US) | 1976-07-27 | — | — | US | disclosed |