SCHEMBL28540662

SCHEMBL28540662

Fc1ccc(C#Cc2ccccc2[SeH])cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.39
NPC1 O15118 2/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
ALDH1A1 P00352 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
HPGD P15428 1/20 0.39
CYP2C19 P33261 1/20 0.39
KMT2A Q03164 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HSD17B10 Q99714 1/20 0.39
APP P05067 1/20 0.37
GRM5 P41594 6/20 0.36
FFAR1 O14842 4/20 0.36
CA12 O43570 3/20 0.35
CA2 P00918 3/20 0.35
CA9 Q16790 3/20 0.35
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL28492391 0.98 NPC1 (0.38) MAPTNPC1KDM4EMEN1ALDH1A1
SCHEMBL28506079 0.83 APP (0.57) MAPTNPC1KDM4EMEN1ALDH1A1
SCHEMBL9305673 0.79 GRM5 (0.51) MAPTNPC1KDM4EMEN1ALDH1A1
SCHEMBL28933437 0.76 FFAR1 (0.53) MAPTNPC1KDM4EMEN1ALDH1A1
SCHEMBL17469612 0.76 MAPT (0.70) MAPTNPC1KDM4EMEN1ALDH1A1
SCHEMBL29428994 0.76 MAPT (0.70) MAPTNPC1KDM4EMEN1ALDH1A1
SCHEMBL29001491 0.76 MAPT (0.39) MAPTNPC1KDM4EMEN1ALDH1A1
SCHEMBL28513835 0.76 MAPT (0.39) MAPTNPC1KDM4EMEN1ALDH1A1
SCHEMBL717468 0.75 APP (0.67) MAPTNPC1KDM4EMEN1ALDH1A1
SCHEMBL18867945 0.75 APP (0.67) MAPTNPC1KDM4EMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110483476-B Process for preparing benzoselenophene compound by catalytic method 绍兴文理学院 2020-11-27 CN disclosed