Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 3/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL717468 | 1.00 | APP (0.67) | APPMAPTFFAR1CA12CA1 | |
| SCHEMBL718949 | 0.88 | GRM5 (0.50) | APPMAPTFFAR1CA12CA1 | |
| SCHEMBL7717366 | 0.88 | GRM5 (0.50) | APPMAPTFFAR1CA12CA1 | |
| SCHEMBL10300106 | 0.88 | GRM5 (0.50) | APPMAPTFFAR1CA12CA1 | |
| Fluoride SCHEMBL31286313 | 0.85 | GRM5 (0.48) | APPMAPTFFAR1CA12CA1 | |
| Charcoal, Activated SCHEMBL31286307 | 0.85 | GRM5 (0.48) | APPMAPTFFAR1CA12CA1 | |
| SCHEMBL2114741 | 0.85 | APP (0.92) | APPMAPTFFAR1CA12CA1 | |
| SCHEMBL20886674 | 0.85 | APP (0.48) | APPMAPTFFAR1CA12CA1 | |
| SCHEMBL5872152 | 0.84 | CYP1A2 (0.48) | APPMAPTFFAR1CA12CA1 | |
| SCHEMBL16741768 | 0.83 | NFE2L2 (0.44) | APPMAPTFFAR1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170137341-A1 | FLUORINATION METHOD | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2017-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170137341-A1 | FLUORINATION METHOD | F13B, PPARG, PGC | APP 3831/4885MAPT 2082/4885FFAR1 217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.