SCHEMBL28540705

SCHEMBL28540705

O=C(CC(=O)OC1CCCCCC1)CC(=O)OC1CCCCCC1

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.53
EPHX1 P07099 2/20 0.52
NAAA Q02083 2/20 0.52
HTT P42858 1/20 0.50
CYP19A1 P11511 2/20 0.47
CA12 O43570 2/20 0.40
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA9 Q16790 2/20 0.40
SMN1; SMN2 Q16637 4/20 0.38
ALDH1A1 P00352 2/20 0.37
KDM4E B2RXH2 1/20 0.37
HPGD P15428 1/20 0.37
HSD17B10 Q99714 1/20 0.37
EPHX2 P34913 1/20 0.37
LMNA P02545 2/20 0.37
MAPT P10636 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
RAB9A P51151 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28553962 1.00 CYP2C19 (0.53) CYP2C19EPHX1NAAAHTTCYP19A1
SCHEMBL242936 0.91 CYP2C19 (0.57) CYP2C19EPHX1NAAAHTTCYP19A1
SCHEMBL17920350 0.91 CYP2C19 (0.57) CYP2C19EPHX1NAAAHTTCYP19A1
SCHEMBL240891 0.88 NAAA (0.53) CYP2C19EPHX1NAAAHTTCYP19A1
SCHEMBL28219616 0.88 EPHX1 (0.55) CYP2C19EPHX1NAAAHTTCYP19A1
SCHEMBL5482663 0.85 NAAA (0.53) CYP2C19EPHX1NAAAHTTCYP19A1
SCHEMBL6835383 0.85 NAAA (0.60) CYP2C19EPHX1NAAAHTTCYP19A1
SCHEMBL3793744 0.84 CYP2C19 (0.52) CYP2C19EPHX1NAAAHTTCYP19A1
SCHEMBL2625648 0.84 CYP2C19 (0.52) CYP2C19EPHX1NAAAHTTCYP19A1
SCHEMBL28385625 0.84 CYP2C19 (0.52) CYP2C19EPHX1NAAAHTTCYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112479843-B Preparation method of 5-methyl-3-cyclohexenone and application thereof in preparation of m-cresol 万华化学集团股份有限公司 2022-08-05 CN disclosed
CN-112479843-A Preparation method of 5-methyl-3-cyclohexenone and application thereof in preparation of m-cresol 万华化学集团股份有限公司 2021-03-12 CN disclosed