Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SCN1A | P35498 | 3/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL285292 | 0.91 | THRB (0.48) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL717851 | 0.85 | THRB (0.37) | THRBTSHRHPGD | |
| SCHEMBL285117 | 0.82 | THRB (0.50) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL285208 | 0.82 | TSHR (0.41) | THRBTSHRSCN1ASCN2ASCN3A | |
| SCHEMBL285778 | 0.79 | THRB (0.47) | THRBTSHRHPGDSCN1ASCN2A | |
| SCHEMBL285620 | 0.78 | THRB (0.49) | THRBTSHRHPGDSCN1ASCN2A | |
| SCHEMBL285105 | 0.75 | TSHR (0.49) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL285067 | 0.75 | TSHR (0.49) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL42562 | 0.72 | THRB (0.58) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL285741 | 0.72 | THRB (0.40) | THRBTSHRSCN1ASCN2ASCN3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427509-A1 | POLYMER COMPOSITION | Contamac Limited (GB) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128266-A1 | POLYMER COMPOSITION | CONTAMAC LIMITED (GB) | 2010-11-11 | — | — | WO | disclosed |