Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CCR1 | P32246 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854478 | 0.84 | ITGB3 (0.46) | MAPTMEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL2854327 | 0.84 | CNR1 (0.58) | MAPTSMN1; SMN2CCR1TRPV1NPSR1 | |
| SCHEMBL2852086 | 0.81 | ITGB3 (0.53) | MAPTTRPV1NPSR1KDM4EALDH1A1 | |
| SCHEMBL2860983 | 0.79 | MAPT (0.49) | MAPTMEN1KMT2ASMN1; SMN2CCR1 | |
| SCHEMBL2723199 | 0.78 | MEN1 (0.78) | MAPTMEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL2723748 | 0.77 | MAPT (0.57) | MAPTMEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL2862263 | 0.76 | MAPT (0.47) | MAPTCCR1TRPV1NPSR1KDM4E | |
| SCHEMBL2880891 | 0.76 | CNR1 (0.54) | MAPTMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL2856146 | 0.76 | CNR1 (0.53) | MAPTMEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL2858063 | 0.75 | MAPT (0.57) | MAPTSMN1; SMN2CCR1TRPV1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |