Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 17/20 | 0.60 |
| ▸ | CDK12 | Q9NYV4 | 17/20 | 0.60 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.45 |
| ▸ | CDK2 | P24941 | 2/20 | 0.45 |
| ▸ | CDK7 | P50613 | 2/20 | 0.45 |
| ▸ | CCNH | P51946 | 2/20 | 0.45 |
| ▸ | MNAT1 | P51948 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.45 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28541025 | 1.00 | CCNK (0.60) | CCNKCDK12CCNA2CDK2CDK7 | |
| SCHEMBL23295753 | 0.85 | CCNK (0.62) | CCNKCDK12CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL28559099 | 0.85 | CCNK (0.62) | CCNKCDK12CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL28547873 | 0.83 | CDK12 (0.44) | CCNKCDK12 | |
| SCHEMBL23292301 | 0.83 | CDK12 (0.44) | CCNKCDK12 | |
| SCHEMBL28543261 | 0.82 | CCNK (0.60) | CCNKCDK12 | |
| SCHEMBL28552948 | 0.82 | CCNK (0.60) | CCNKCDK12 | |
| SCHEMBL28557319 | 0.82 | CDK12 (0.57) | CCNKCDK12CCNA2CDK2CDK7 | |
| SCHEMBL28543260 | 0.82 | CCNK (0.60) | CCNKCDK12 | |
| SCHEMBL28551451 | 0.82 | CDK12 (0.57) | CCNKCDK12CCNA2CDK2CDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112638373-A | Cyclin-dependent kinase inhibitors | 金耐特生物制药公司 | 2021-04-09 | — | — | CN | disclosed |