Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 2/20 | 0.62 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.57 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.57 |
| ▸ | CCR6 | P51684 | 8/20 | 0.55 |
| ▸ | JAK3 | P52333 | 2/20 | 0.53 |
| ▸ | JAK2 | O60674 | 1/20 | 0.53 |
| ▸ | DPP4 | P27487 | 4/20 | 0.50 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.50 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.50 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.49 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23295753 | 1.00 | CCNK (0.62) | CCNKCDK12CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1119515 | 0.93 | CCNK (0.55) | CCNKCDK12CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL21853948 | 0.92 | CCNK (0.61) | CCNKCDK12CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL21853973 | 0.90 | CCNK (0.53) | CCNKCDK12CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL28541025 | 0.85 | CCNK (0.60) | CCNKCDK12CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL28541024 | 0.85 | CCNK (0.60) | CCNKCDK12CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1036415 | 0.83 | CYP3A4 (0.58) | CCNKCDK12CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL23292365 | 0.83 | CYP3A4 (0.58) | CCNKCDK12CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1036416 | 0.83 | CYP3A4 (0.58) | CCNKCDK12CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL2424299 | 0.82 | CCNK (0.47) | CCNKCDK12CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112638373-A | Cyclin-dependent kinase inhibitors | 金耐特生物制药公司 | 2021-04-09 | — | — | CN | disclosed |