Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.74 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.70 |
| ▸ | PPARG | P37231 | 7/20 | 0.70 |
| ▸ | PPARD | Q03181 | 7/20 | 0.70 |
| ▸ | PPARA | Q07869 | 7/20 | 0.70 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.70 |
| ▸ | TSHR | P16473 | 5/20 | 0.70 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | TLR2 | O60603 | 2/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.70 |
| ▸ | FABP4 | P15090 | 2/20 | 0.70 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.70 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.70 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.70 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | ESR1 | P03372 | 1/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.70 |
| ▸ | PDE4A | P27815 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL536407 | 1.00 | AKR1B1 (0.74) | AKR1B1GPR84PPARGPPARDPPARA | |
| Sebacic Acid SCHEMBL28546319 | 0.97 | GPR84 (0.75) | AKR1B1GPR84PPARGPPARDPPARA | |
| Octanedioate SCHEMBL28595812 | 0.97 | GPR84 (0.75) | AKR1B1GPR84PPARGPPARDPPARA | |
| Myristic Acid SCHEMBL9559499 | 0.92 | GPR84 (0.85) | AKR1B1GPR84PPARGPPARDPPARA | |
| Palmitic Acid SCHEMBL28303608 | 0.92 | GPR84 (0.85) | AKR1B1GPR84PPARGPPARDPPARA | |
| Valeric Acid SCHEMBL49002 | 0.92 | AKR1B1 (0.70) | AKR1B1GPR84PPARGPPARDPPARA | |
| Stearic Acid SCHEMBL27793317 | 0.90 | GPR84 (0.81) | AKR1B1GPR84PPARGPPARDPPARA | |
| Hexanoate SCHEMBL4970439 | 0.89 | AKR1B1 (0.84) | AKR1B1GPR84PPARGPPARDPPARA | |
| Hexanoate SCHEMBL2929839 | 0.89 | AKR1B1 (0.84) | AKR1B1GPR84PPARGPPARDPPARA | |
| Adipic Acid SCHEMBL7106977 | 0.89 | AKR1B1 (0.84) | AKR1B1GPR84PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118703156-A | Reactive polyurethane hot melt adhesive and preparation method thereof | 华大化学集团有限公司 | 2024-09-27 | — | — | CN | disclosed |
| CN-112609201-B | Method for synthesizing carbonic acid diester and sebacic acid diester in pair | 万华化学(四川)有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-112609201-A | Method for pair-wise synthesizing carbonic diester and sebacic diester | 万华化学(四川)有限公司 | 2021-04-06 | — | — | CN | disclosed |