SCHEMBL28542204

SCHEMBL28542204

CCn1nc(C(=O)O)c(Cl)c1-c1ccc(OC(C)C(F)(F)F)cc1OC

nearest known ligand 0.65

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ RORC P51449 20/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21607688 0.90 RORC (0.62) RORC
SCHEMBL21605631 0.85 RORC (0.69) RORC
SCHEMBL21605666 0.85 RORC (0.69) RORC
SCHEMBL21605660 0.85 RORC (0.69) RORC
SCHEMBL23189844 0.85 RORC (0.65) RORC
SCHEMBL21607924 0.85 RORC (0.65) RORC
SCHEMBL28535154 0.85 RORC (0.65) RORC
SCHEMBL23189683 0.83 RORC (0.67) RORC
SCHEMBL23189679 0.83 RORC (0.67) RORC
SCHEMBL28538776 0.81 RORC (0.70) RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112566901-A Phenyl-substituted pyrazoles as modulators of ROR γ t 詹森药业有限公司 2021-03-26 — — CN disclosed
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