Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 17/20 | 0.56 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.40 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28542484 | 0.93 | EGFR (0.66) | EGFRFGFR3KDRFGFR1FGFR2 | |
| SCHEMBL28529613 | 0.91 | EGFR (0.52) | EGFR | |
| SCHEMBL25144480 | 0.89 | EGFR (0.59) | EGFR | |
| SCHEMBL28538542 | 0.88 | EGFR (0.59) | EGFR | |
| SCHEMBL30626539 | 0.88 | EGFR (0.51) | EGFR | |
| SCHEMBL28530485 | 0.88 | EGFR (0.51) | EGFR | |
| SCHEMBL28531358 | 0.88 | EGFR (0.59) | EGFRFGFR3KDRFGFR1FGFR2 | |
| SCHEMBL30626523 | 0.88 | EGFR (0.59) | EGFRFGFR3KDRFGFR1FGFR2 | |
| SCHEMBL22804404 | 0.87 | EGFR (0.49) | EGFR | |
| SCHEMBL30626547 | 0.87 | EGFR (0.49) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513029-B | Nitrogen-containing aryl phosphorus oxide derivative, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-10-24 | — | — | CN | disclosed |
| CN-112513029-A | Nitrogen-containing aryl phosphorus oxide derivative, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2021-03-16 | — | — | CN | disclosed |