Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 16/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856191 | 0.90 | CCR1 (0.80) | CCR1NPSR1KDM4E | |
| SCHEMBL2860195 | 0.90 | CCR1 (0.70) | CCR1LMNAHPGDNPSR1KDM4E | |
| SCHEMBL2854432 | 0.89 | CCR1 (0.68) | CCR1LMNAHPGD | |
| SCHEMBL2854461 | 0.89 | CCR1 (0.75) | CCR1LMNAHPGDNPSR1KDM4E | |
| SCHEMBL2859933 | 0.89 | CCR1 (0.80) | CCR1LMNAHPGDNPSR1HSP90AA1 | |
| SCHEMBL2859642 | 0.88 | CCR1 (0.73) | CCR1HPGDKDM4EMAPT | |
| SCHEMBL12315399 | 0.86 | CCR1 (0.83) | CCR1 | |
| SCHEMBL2854971 | 0.85 | CCR1 (0.66) | CCR1NPSR1KDM4E | |
| SCHEMBL2858942 | 0.84 | CCR1 (0.82) | CCR1NPSR1KDM4EHSP90AA1MAPT | |
| SCHEMBL2854324 | 0.84 | CCR1 (0.51) | CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |