Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 14/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.56 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.56 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.56 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.56 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.56 |
| ▸ | MAP3K2 | Q9Y2U5 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2860195 | 0.94 | CCR1 (0.70) | CCR1KDM4EALDH1A1HPGD | |
| SCHEMBL2856191 | 0.92 | CCR1 (0.80) | CCR1KDM4EALDH1A1 | |
| SCHEMBL2854060 | 0.91 | KDM4E (0.65) | CCR1KDM4EALDH1A1MAPK14POLB | |
| SCHEMBL2854461 | 0.91 | CCR1 (0.75) | CCR1KDM4EALDH1A1HPGD | |
| SCHEMBL2854432 | 0.91 | CCR1 (0.68) | CCR1HPGD | |
| SCHEMBL2859933 | 0.91 | CCR1 (0.80) | CCR1MAPTHPGD | |
| SCHEMBL2860213 | 0.90 | KDM4E (0.73) | CCR1KDM4EALDH1A1MAPK14POLB | |
| SCHEMBL2850143 | 0.88 | CCR1 (0.85) | CCR1KDM4EMAPK14POLBMAPT | |
| SCHEMBL2860538 | 0.88 | KDM4E (0.61) | CCR1KDM4EALDH1A1MAPK14POLB | |
| SCHEMBL2854971 | 0.88 | CCR1 (0.66) | CCR1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |