Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 1/20 | 0.69 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.57 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852065 | 0.85 | SMN1; SMN2 (0.74) | BRAFKCNK3SMN1; SMN2HTTLMNA | |
| SCHEMBL27817425 | 0.83 | MEN1 (0.68) | KCNK3SMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL3933255 | 0.82 | BRAF (1.00) | BRAFMAPTL3MBTL1 | |
| SCHEMBL259177 | 0.81 | TDP1 (0.78) | BRAFKCNK3TSHRSMN1; SMN2HTT | |
| SCHEMBL30678437 | 0.80 | RXFP1 (0.58) | BRAFKCNK3TSHRHTTLMNA | |
| SCHEMBL27181470 | 0.80 | MEN1 (0.73) | KCNK3SMN1; SMN2HTTLMNAMAPT | |
| SCHEMBL1520222 | 0.79 | KCNK3 (0.76) | KCNK3TSHRSMN1; SMN2HTTLMNA | |
| SCHEMBL10940026 | 0.79 | KCNK3 (0.81) | KCNK3TSHRSMN1; SMN2HTTLMNA | |
| SCHEMBL24448266 | 0.78 | KMT2A (0.61) | KCNK3TSHRSMN1; SMN2HTTLMNA | |
| SCHEMBL14372350 | 0.78 | RXFP1 (0.66) | BRAFKCNK3LMNAHIF1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |