Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.74 |
| ▸ | MEN1 | O00255 | 3/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.59 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.59 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.59 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | BRAF | P15056 | 1/20 | 0.57 |
| ▸ | NAMPT | P43490 | 1/20 | 0.55 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27817425 | 0.87 | MEN1 (0.68) | SMN1; SMN2MEN1KMT2ALMNAKCNK3 | |
| SCHEMBL2854355 | 0.85 | BRAF (0.69) | SMN1; SMN2MEN1KMT2ALMNAKCNK3 | |
| SCHEMBL12793766 | 0.82 | GAA (0.71) | SMN1; SMN2MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL7680266 | 0.80 | ADORA3 (0.75) | SMN1; SMN2MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL30926929 | 0.80 | LMNA (0.76) | SMN1; SMN2MEN1KMT2ALMNAKCNK3 | |
| SCHEMBL27180161 | 0.80 | LMNA (0.76) | SMN1; SMN2MEN1KMT2ALMNAKCNK3 | |
| SCHEMBL259421 | 0.79 | KCNK3 (0.86) | SMN1; SMN2MEN1KMT2ALMNAKCNK3 | |
| SCHEMBL2862662 | 0.79 | SMN1; SMN2 (0.65) | SMN1; SMN2MEN1KMT2AKCNK3ALDH1A1 | |
| SCHEMBL14372391 | 0.79 | CA1 (0.74) | MEN1KMT2ALMNAALDH1A1ADORA3 | |
| SCHEMBL12021948 | 0.79 | KCNK3 (0.87) | SMN1; SMN2MEN1KMT2ALMNAKCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |