SCHEMBL28543775

SCHEMBL28543775

CCOC(=O)c1ccccc1C(=O)OC(=O)c1ccccc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.72
ALDH1A1 P00352 5/20 0.57
HSD17B10 Q99714 1/20 0.57
SMN1; SMN2 Q16637 5/20 0.53
NPC1 O15118 3/20 0.53
GAA P10253 3/20 0.53
RAB9A P51151 2/20 0.53
CDC25B P30305 1/20 0.53
CASP3 P42574 1/20 0.52
SENP8 Q96LD8 1/20 0.52
SENP7 Q9BQF6 1/20 0.52
SENP6 Q9GZR1 1/20 0.52
HTT P42858 1/20 0.52
LMNA P02545 2/20 0.51
KMT2A Q03164 5/20 0.51
MEN1 O00255 3/20 0.51
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
HPGD P15428 1/20 0.49
MAPT P10636 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28552669 0.88 TSHR (0.56) TSHRALDH1A1HSD17B10SMN1; SMN2NPC1
SCHEMBL11051593 0.88 TSHR (0.75) TSHRALDH1A1HSD17B10CDC25BLMNA
SCHEMBL11769775 0.87 SMN1; SMN2 (0.66) TSHRALDH1A1SMN1; SMN2NPC1GAA
Alcohol SCHEMBL4578564 0.87 TSHR (0.52) TSHRALDH1A1HSD17B10SMN1; SMN2NPC1
Diethyl Phthalate SCHEMBL28775845 0.87 TSHR (0.95) TSHRALDH1A1HSD17B10CDC25BLMNA
Diethyl Phthalate SCHEMBL19252611 0.87 TSHR (0.95) TSHRALDH1A1HSD17B10CDC25BLMNA
SCHEMBL28564455 0.87 ALDH1A1 (0.74) TSHRALDH1A1HSD17B10RAB9ALMNA
SCHEMBL28547104 0.87 TSHR (0.54) TSHRALDH1A1HSD17B10SMN1; SMN2NPC1
Diethyl Phthalate SCHEMBL27284492 0.86 TSHR (0.78) TSHRALDH1A1HSD17B10SMN1; SMN2NPC1
Diethyl Phthalate SCHEMBL28168029 0.85 TSHR (0.91) TSHRALDH1A1HSD17B10CDC25BLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109553706-B Catalyst component for olefin polymerization, catalyst and application 中国石油化工股份有限公司 2021-04-13 CN claimed
CN-109553703-B Catalyst component for olefin polymerization and preparation method thereof 中国石油化工股份有限公司 2021-04-13 CN claimed
CN-109553711-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-04-13 CN claimed
CN-109553703-B Catalyst component for olefin polymerization and preparation method thereof 中国石油化工股份有限公司 2021-04-13 CN disclosed
CN-109553706-B Catalyst component for olefin polymerization, catalyst and application 中国石油化工股份有限公司 2021-04-13 CN disclosed
CN-109553711-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-04-13 CN disclosed