⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6747192 | 1.00 | — | — | |
| SCHEMBL8507540 | 1.00 | — | — | |
| SCHEMBL31017583 | 0.95 | ALDH1A1 (0.30) | — | |
| SCHEMBL19971177 | 0.95 | ALDH1A1 (0.30) | — | |
| SCHEMBL2790379 | 0.95 | ALDH1A1 (0.30) | — | |
| SCHEMBL8763394 | 0.95 | ALDH1A1 (0.30) | — | |
| SCHEMBL1003911 | 0.95 | — | — | |
| SCHEMBL1812050 | 0.95 | — | — | |
| SCHEMBL23914 | 0.94 | — | — | |
| SCHEMBL458413 | 0.89 | ALDH1A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024104322-A1 | 15-PGDH INHIBITOR | 武汉人福创新药物研发中心有限公司 | 2024-05-23 | — | — | WO | claimed |
| CN-118027058-A | 15-PGDH inhibitors | 武汉人福创新药物研发中心有限公司 | 2024-05-14 | — | — | CN | claimed |
| CN-114426511-A | Method for preparing chiral spiro [2.4] heptane compounds through palladium-catalyzed asymmetric cycloaddition reaction | 山东大学 | 2022-05-03 | — | — | CN | claimed |
| EP-3642264-A1 | CURABLE SILICONE COMPOSITION AND APPLICATIONS AND USES THEREOF | Momentive Performance Materials Inc. (US) | 2020-04-29 | — | — | EP | claimed |
| US-10385210-B2 | Curable silicone composition and applications and uses thereof | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2019-08-20 | — | — | US | claimed |
| US-10287400-B2 | Curable silicone composition and applications and uses thereof | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2019-05-14 | — | — | US | claimed |
| EP-3443027-A1 | CURABLE SILICONE COMPOSITION AND APPLICATIONS AND USES THEREOF | Momentive Performance Materials Inc. (US) | 2019-02-20 | — | — | EP | claimed |
| WO-2018236679-A1 | CURABLE SILICONE COMPOSITION AND APPLICATIONS AND USES THEREOF | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2018-12-27 | — | — | WO | claimed |
| US-20180362764-A1 | CURABLE SILICONE COMPOSITION AND APPLICATIONS AND USES THEREOF | MOMENTIVE PERFORMANCE MATERIALS INC. | 2018-12-20 | — | — | US | claimed |
| US-20170298188-A1 | CURABLE SILICONE COMPOSITION AND APPLICATIONS AND USES THEREOF | MOMENTIVE PERFORMANCE MATERIALS INC. | 2017-10-19 | — | — | US | claimed |
| US-9216960-B2 | Spiro[2.4]heptanes for treatment of Flaviviridae infections | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2015-12-22 | — | — | US | claimed |
| US-20150079036-A1 | Spiro[2.4]heptanes for Treatment of Flaviviridae Infections | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2015-03-19 | — | — | US | claimed |
| US-8946242-B2 | Spiro[2.4]heptanes for treatment of flaviviridae infections | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2015-02-03 | — | — | US | claimed |
| US-8921384-B2 | Spiro[2.4]heptanes for treatment of flaviviridae infections | UNVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2014-12-30 | — | — | US | claimed |
| EP-2814816-A2 | SPIRO [2.4]HEPTANES FOR TREATMENT OF FLAVIVIRIDAE INFECTIONS | University Of Georgia Research Foundation, Inc. (US) | 2014-12-24 | — | — | EP | claimed |
| US-20140140957-A1 | Spiro[2.4]heptanes for Treatment of Flaviviridae Infections | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2014-05-22 | — | — | US | claimed |
| US-20140140958-A1 | Spiro[2.4]heptanes for Treatment of Flaviviridae Infections | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2014-05-22 | — | — | US | claimed |
| US-8673926-B2 | Spiro[2.4]heptanes for treatment of flaviviridae infections | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2014-03-18 | — | — | US | claimed |
| US-20130224152-A1 | Spiro[2.4]heptanes for Treatment of Flaviviridae Infections | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2013-08-29 | — | — | US | claimed |
| WO-2013123138-A2 | SPIRO [2.4]HEPTANES FOR TREATMENT OF FLAVIVIRIDAE INFECTIONS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2013-08-22 | — | — | WO | claimed |