Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL397072 | 0.87 | MGLL (0.51) | MGLLNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL394888 | 0.84 | MGLL (0.55) | MGLLNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL11766069 | 0.81 | NPC1 (0.72) | MGLLNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL3792767 | 0.79 | MGLL (0.61) | MGLLNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL5947042 | 0.79 | NPC1 (0.64) | MGLLNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL13104562 | 0.78 | NPC1 (0.60) | MGLLNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL23483449 | 0.78 | SMN1; SMN2 (0.75) | MGLLNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL15603508 | 0.77 | MGLL (0.67) | MGLLNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL25856302 | 0.77 | MAPT (0.60) | MGLLNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL5852207 | 0.76 | POLB (0.68) | MGLLNPC1RAB9ASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107501099-B | Modulators of ATP-binding cassette transporters | 沃泰克斯药物股份有限公司 | 2021-03-19 | — | — | CN | disclosed |