Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.48 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.48 |
| ▸ | ITGAL | P20701 | 2/20 | 0.48 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.48 |
| ▸ | CCKBR | P32239 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854499 | 0.84 | ALDH1A1 (0.58) | ALDH1A1MAPK1MAPT | |
| SCHEMBL2855120 | 0.79 | MAPT (0.51) | MEN1KMT2AHCRTR1ALDH1A1MAPT | |
| SCHEMBL3993086 | 0.75 | ITGB2 (0.65) | MEN1KMT2AHCRTR1ALDH1A1MAPT | |
| SCHEMBL3993084 | 0.75 | ITGB2 (0.65) | MEN1KMT2AHCRTR1ALDH1A1MAPT | |
| SCHEMBL27703075 | 0.75 | KMT2A (0.71) | MEN1KMT2AHCRTR1MAPTITGB2 | |
| SCHEMBL21001595 | 0.74 | KMT2A (0.81) | MEN1KMT2AHCRTR1MAPTTHRB | |
| SCHEMBL21001594 | 0.74 | KMT2A (0.81) | MEN1KMT2AHCRTR1MAPTTHRB | |
| SCHEMBL31520097 | 0.74 | KMT2A (0.81) | MEN1KMT2AHCRTR1MAPTTHRB | |
| SCHEMBL21001593 | 0.73 | KMT2A (0.76) | MEN1KMT2AHCRTR1MAPTTHRB | |
| SCHEMBL21001592 | 0.73 | KMT2A (0.76) | MEN1KMT2AHCRTR1MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |