Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA5 | P08648 | 1/20 | 0.43 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.43 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.43 |
| ▸ | KLRK1 | P26718 | 4/20 | 0.41 |
| ▸ | MICA | Q29983 | 4/20 | 0.41 |
| ▸ | RAET1L | Q5VY80 | 3/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
| ▸ | PHGDH | O43175 | 1/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19283678 | 0.87 | ITGA5 (0.44) | ITGA5ITGB6ITGB8KLRK1MICA | |
| SCHEMBL19283810 | 0.86 | KLRK1 (0.53) | ITGA5ITGB6ITGB8KLRK1MICA | |
| SCHEMBL21821288 | 0.86 | KLRK1 (0.52) | ITGA5ITGB6ITGB8KLRK1MICA | |
| SCHEMBL19283862 | 0.86 | KLRK1 (0.52) | ITGA5ITGB6ITGB8KLRK1MICA | |
| SCHEMBL21821304 | 0.85 | HRH4 (0.49) | ITGA5ITGB6ITGB8KLRK1MICA | |
| SCHEMBL21821293 | 0.84 | ITGA5 (0.46) | ITGA5ITGB6ITGB8KLRK1MICA | |
| SCHEMBL21821319 | 0.84 | ITGA5 (0.49) | ITGA5ITGB6ITGB8KLRK1MICA | |
| SCHEMBL19283725 | 0.84 | ITGA5 (0.48) | ITGA5ITGB6ITGB8KLRK1MICA | |
| SCHEMBL19283627 | 0.83 | ITGA5 (0.46) | ITGA5ITGB6ITGB8KLRK1MICA | |
| Iodide SCHEMBL19283626 | 0.83 | ITGA5 (0.46) | ITGA5ITGB6ITGB8KLRK1MICA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109153667-B | Novel potassium channel inhibitors | 阿塞西翁制药公司 | 2021-04-02 | — | — | CN | claimed |
| CN-109153667-B | Novel potassium channel inhibitors | 阿塞西翁制药公司 | 2021-04-02 | — | — | CN | disclosed |