Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | HRH1 | P35367 | 5/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21142100 | 0.79 | KDM4E (0.49) | HRH1TAAR1KDM4E | |
| SCHEMBL31081656 | 0.79 | KDM4E (0.49) | HRH1TAAR1KDM4E | |
| SCHEMBL8753243 | 0.79 | HSPA5 (0.52) | HRH1CYP2D6CHRM1HTR2AKCNH2 | |
| SCHEMBL8828290 | 0.79 | HRH1 (0.40) | HRH1CYP2D6CHRM1HTR2AKCNH2 | |
| SCHEMBL22263575 | 0.79 | CYP3A4 (0.39) | HRH1CYP2D6CHRM1HTR2AKCNH2 | |
| SCHEMBL28234969 | 0.78 | POLB (0.52) | CYP2D6CYP3A4CYP1A2CYP2C19HTR2C | |
| SCHEMBL21142103 | 0.78 | KDM4E (0.48) | HRH1TAAR1KDM4E | |
| SCHEMBL15926013 | 0.76 | CYP1A2 (0.43) | HRH1CYP2D6CYP3A4CYP1A2CYP2C19 | |
| SCHEMBL28244247 | 0.76 | ADRA2A (0.50) | HRH1CYP2D6CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL25482269 | 0.75 | CYP11B1 (0.40) | HTTCYP11B1CYP11B2CYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112661696-A | Green synthesis method of multi-aryl substituted methanol | 华东理工大学 | 2021-04-16 | — | — | CN | disclosed |