Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK12 | Q9NYV4 | 18/20 | 1.00 |
| ▸ | CCNK | O75909 | 17/20 | 1.00 |
| ▸ | CDK7 | P50613 | 12/20 | 0.64 |
| ▸ | CCNH | P51946 | 12/20 | 0.64 |
| ▸ | MNAT1 | P51948 | 12/20 | 0.64 |
| ▸ | CCNA2 | P20248 | 11/20 | 0.64 |
| ▸ | CDK2 | P24941 | 11/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29777694 | 1.00 | CDK12 (1.00) | CDK12CCNKCDK7CCNHMNAT1 | |
| SCHEMBL22895491 | 1.00 | CDK12 (1.00) | CDK12CCNKCDK7CCNHMNAT1 | |
| SCHEMBL29777697 | 0.87 | CDK12 (1.00) | CDK12CCNKCDK7CCNHMNAT1 | |
| SCHEMBL22895532 | 0.87 | CDK12 (1.00) | CDK12CCNKCDK7CCNHMNAT1 | |
| SCHEMBL28545656 | 0.80 | CCNK (0.66) | CDK12CCNKCDK2 | |
| SCHEMBL28545658 | 0.80 | CCNK (0.66) | CDK12CCNKCDK2 | |
| SCHEMBL29777723 | 0.78 | CCNK (1.00) | CDK12CCNKCDK7CCNHMNAT1 | |
| SCHEMBL22895497 | 0.78 | CCNK (1.00) | CDK12CCNKCDK7CCNHMNAT1 | |
| SCHEMBL23063677 | 0.78 | CDK7 (1.00) | CDK12CCNKCDK7CCNHMNAT1 | |
| SCHEMBL23002982 | 0.78 | CDK7 (1.00) | CDK12CCNKCDK7CCNHMNAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112638373-A | Cyclin-dependent kinase inhibitors | 金耐特生物制药公司 | 2021-04-09 | — | — | CN | disclosed |