Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 2/20 | 0.66 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.66 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.52 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.48 |
| ▸ | OGA | O60502 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 8/20 | 0.45 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.45 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 3/20 | 0.44 |
| ▸ | FLT3 | P36888 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28545658 | 1.00 | CCNK (0.66) | CCNKCDK12HRH4CXCR4OGA | |
| SCHEMBL23292251 | 0.85 | CCNK (0.62) | CCNKCDK12HRH4MAPK10MAPK9 | |
| SCHEMBL22895802 | 0.85 | CCNK (0.62) | CCNKCDK12HRH4MAPK10MAPK9 | |
| SCHEMBL23174113 | 0.81 | HRH4 (0.70) | CCNKCDK12HRH4CXCR4OGA | |
| SCHEMBL22895491 | 0.80 | CDK12 (1.00) | CCNKCDK12CDK2 | |
| SCHEMBL22895532 | 0.80 | CDK12 (1.00) | CCNKCDK12CDK2 | |
| SCHEMBL29777694 | 0.80 | CDK12 (1.00) | CCNKCDK12CDK2 | |
| SCHEMBL29777697 | 0.80 | CDK12 (1.00) | CCNKCDK12CDK2 | |
| SCHEMBL28544359 | 0.80 | CDK12 (1.00) | CCNKCDK12CDK2 | |
| SCHEMBL1090709 | 0.79 | CCNK (0.53) | CCNKCDK12HRH4CXCR4MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112638373-A | Cyclin-dependent kinase inhibitors | 金耐特生物制药公司 | 2021-04-09 | — | — | CN | disclosed |